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MARQUIS is the first FDA-approved treatment for equine protozoal myeloencephalitis (EPM).
Ponazuril, the active ingredient in MARQUIS, crosses the blood/brain barrier to reach the central nervous system where it kills Sarcocystis neurona and stops the parasite from inflicting further damage to the central nervous system. Concentrations achieved in the CSF at steady state were shown to kill 94% of merozoites in cell culture.
MARQUIS is easy to administer and safe when used as directed.